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Kidney Cancer - interview with Brian Rini, MD, at ASCO 2012
At the American Society of Clinical Oncology (ASCO) 2012, Brian Rini, MD, Cleveland Clinic, discusses updates on axitinib. Axitinib (AG013736; trade name Inlyta) is a small molecule tyrosine kinase inhibitor developed by Pfizer. It inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, platelet derived growth factor receptor (PDGFR), and cKIT (CD117). It has been shown to significantly inhibit growth of breast cancer in xenograft models and has been successful in trials with renal cell carcinoma (RCC) and several other tumor t...
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